| About CATHGEN |
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History & Goals
The sequencing of the human genome has provided the template on which major discoveries of cause, treatment and prognosis of disease will be made. Identification of genes, their functions, and their variability will provide a valuable opportunity to investigate the role of genes in disease and especially coronary heart disease, the most common worldwide cause of death.
The CATHGEN Research Project (see the Protocol Collaborators from the Department of Medicine, including the Division of Cardiology, the Duke Cardiac Catheterization Laboratory, and from the Duke Databank, the Duke Clinical Research Institute (DCRI) and the Center for Human Genetics (CHG), created and continue to expand CATHGEN’S sample library and integrated database. The Investigators invite collaboration, particularly with Duke faculty and fellows, to maximize the scientific value of the project. CATHGEN offers DNA, RNA and plasma samples and a database of genetic information, blood biochemical markers, clinical information, and clinical follow-up to investigate the relationships between genes, cardiovascular disease and outcomes. |
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CATHGEN Executive Committee
The CATHGEN Executive Committee is composed of nine individuals, including a Steering Group of three individuals included as Co-investigators on the CATHGEN parent IRB. The Executive Committee maintains and directs the project and makes decisions about use of CATHGEN resources. The CATHGEN Investigators recognize and appreciate the contribution made by individuals willing to participate as research subjects in the CATHGEN project. The investigators are committed to the highest level of confidentiality and protection of subject privacy. No identifying information regarding subjects will be shared with any collaborators outside of Duke Medical Center. Information shared by researchers within Duke will include the minimum necessary for the conduct of the research project. Review and approval by the Duke IRB will be required for all studies utilizing the resources of the project. The project has received a "Certificate of Confidentiality"
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DHTS Web Services
DUKE UNIVERSITY
SCHOOL OF MEDICINE
DUKEHEALTH.ORG
) is a resource for the investigation of genes associated with coronary heart disease and related disorders. The project began collecting DNA and serum samples in December of 2000 from consenting research subjects undergoing cardiac catheterization at Duke University Medical Center.